TACKLE INFECTIOUS DISEASES AND ANTIMICROBIAL RESISTANCE
Infectious diseases are a major global health problem, accounting for one in five deaths worldwide and a quarter of the annual global disease burden (in terms of years of life lost due to premature mortality or physical disabilities).
The annual global mortality associated with antimicrobial resistance is currently estimated at 5 million deaths. It is expected to double and cost the global economy up to $100 trillion within the next 30 years according to the World Health Organization (WHO).
To address this urgent issue and save lives, it is essential to have accurate and rapid diagnostic solutions to detect (drug-resistant) pathogens, for guiding treatment decisions and public health interventions. The Deeplex® engineering, developed by GenoScreen, has been specifically designed to achieve this goal.
GET CLINICALLY ACTIONABLE INFORMATION FROM MICROBIAL DNA
Deeplex® engineering combines deep multi-target DNA sequencing, automated bioinformatic analysis and easy reporting for microbial identification and extensive detection of drug resistance.
This innovative technology offers several key advantages:
- Culture-free: Can be performed directly from clinical specimens or isolates.
- Extensive: all-in-one design combining multiple drug resistance, bacterial speciation and strain genotyping targets, for extensive diagnosis and monitoring.
- Sensitive: Detection of minority variants and mixed infections.
- Fast: Results can be obtained within 2 days, starting from clinical samples.
- Accessible: Automated analytic tools and reporting; no need for bioinformatics skills.
- Cost-effective: Higher sample multiplexing than whole genome sequencing; no need for culturing (depending on bacterial load).
POWERFUL SOLUTIONS FOR CLINICIANS AND RESEARCHERS
By overcoming major limitations of conventional phenotypic and molecular testing, Deeplex® products represent novel powerful solutions for improving the clinical management and the monitoring of drug resistant infectious diseases .
Sources
World Health Organization
Antimicrobial resistance, WHO, 2021: https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance
